High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis.

نویسندگان

  • Anastácio Q Sousa
  • Mércia S Frutuoso
  • Elisabete A Moraes
  • Richard D Pearson
  • Margarida M L Pompeu
چکیده

We report for the first time the successful use of fluconazole to treat cutaneous leishmaniasis due to Leishmania braziliensis. We used escalating doses from 5 to 8 mg/kg per day. At a dose of 5 mg/kg per day, 75% patients were cured, and at 8 mg/kg per day, the cure rate was 100%. Fluconazole was well tolerated.

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منابع مشابه

Reply to Torres and Suárez

TO THE EDITOR—We appreciate Drs Torres and Suárez’s interest in our article, “High-Dose Oral Fluconazole Therapy Effective for Cutaneous Leishmaniasis Due to Leishmania (Vianna) braziliensis” [1]. They refer to evidence of Leishmania amazonensis isolated from human as well as domestic and wild reservoir hosts from the state of Ceará and suggest it is an important etiologic agent of cutaneous le...

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 53 7  شماره 

صفحات  -

تاریخ انتشار 2011